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U.S. ARTIFICIAL DISC REPLACEMENT MARKET TO REACH $440 MILLION BY 2013

Life Science Intelligence expects the U.S. market for artificial disc replacement products to grow by more than 40% annually through 2013

HUNTINGTON BEACH, Calif.-May 14, 2008--(BUSINESS WIRE)--According to a new Life Science Intelligence (LSI) Report, 2008 U.S. Markets for Spinal Disc Repair and Replacement Technologies, the U.S. market for artificial disc replacement will grow from $55 million in 2007 to $440 million by 2013.

To date, the growth of the U.S. market for artificial disc replacements has been disappointing. Initially, these technologies were expected to rapidly penetrate the market for spinal fusion patients due to their potential to preserve motion, limit further degeneration, and avoid the need for fusion. Since the approval of DePuy Spine’s Charité for lumbar disc replacement in October 2004 however, growth has been restrained by reimbursement challenges, limited long-term data, and the need to use an anterior approach for lumbar disc replacement.

Despite these challenges, manufacturers continue to pursue the enormous opportunity in artificial discs, and by 2013, a number of products should be approved which will feature different designs and allow alternative approaches to the lumbar spine. According to this new report by Life Science Intelligence (LSI), growth in lumbar disc replacements will increase due to positive developments in reimbursement, favorable clinical results, and the use of alternatives to the anterior approach.

In the market for cervical disc replacements, where growth has also been limited by reimbursement challenges and clinical concerns, the introduction of devices with different designs, the use of a familiar approach, and the increasing performance of multiple-level replacements during a single procedure will drive greater adoption.

As analyzed in this report, emerging markets such as annulus repair and nucleus repair/replacement could begin to limit the growth of artificial discs towards the end of the forecast period. Annulus repair, which can be used as a simple adjunct to discectomy, will see rapid adoption through 2013, particularly among newer surgeons. The market for nucleus replacement products, which should see some steady growth after 2010, is expected to grow substantially after the introduction of biological repair products, which could occur as early as 2012. By reducing the need for total disc replacement, these technologies will contribute to slower growth in the market for artificial discs after 2013.

2008 U.S. Markets for Spinal Disc Repair and Replacement Technologies covers artificial disc replacements for the lumbar and cervical spine, annulus repair, and nucleus repair/replacement technologies. Over 40 industry competitors are covered in the report, including select companies such as: Abbott Spine (ABT), Anulex Technologies, Biomet, Cervitech, DePuy Spine (JNJ), LDR Spine, Medtronic Sofamor Danek (MDT), NuVasive (NUVA), Orthofix (OFIX), Orthopeutics, Spinal Motion, Stryker Spine (SYK), Synthes (SWX: SYST.VX), Vertebron, and Zimmer Spine (ZMH).

About Life Science Intelligence (LSI)

LSI delivers high-quality market data and information to medical technology executives, entrepreneurs, and investors. LSI produces the EMT (Emerging Medical Technologies) Database, medtech market reports, and provides custom research services, including market assessments and physician surveys. In addition, LSI partners with top-tier information companies such as Health Research International (HRI) and Windhover/Medtech Insight to distribute their high-end information products. www.LSintelligence.com.

Contact:
Life Science Intelligence, Huntington Beach
Scott Pantel, 714 847 3540
scott@LSintelligence.com
www.lsintelligence.com
www.emergingmedicaltechnologies.com